Biocomputing Unit / Research Activities

RESEARCH

The group works along five lines of research, combining structural biology and scientific computing approaches.

Structural biology by 3D electron microscopy
	Experimental activities Procaryotic replicative helicases Eucaryotic replicative helicase models The Large T Antigen of Simian Virus 40 MCM, the study of Archaeal helicases
	Methodological developments
Structural Bioinformatics
	Development of new databases
Integrating Structural Information
	SPI-EM Detecting the CATH superfamily in 3D-EM maps
	Flexible fitting in 3D-EM
Functional Bioinformatics
	Data Mining, Text Mining and Gene Expression
Scientific Computing
	Multidimensional Image Processing
	Pattern recognition and machine learning
	Query by Content in databases
	Grid-oriented computing
	Database mediation

Research projects